Dr. Kushnir discusses a research publication in Reproductive Biology & Endocrinology that compares the efficacy of large- versus small-sized needles for egg retrieval. Reprod Biol Endocrinol 2013;11:22.
Background: This study was designed to determine whether small diameter needles for oocyte retrieval alter oocyte yields in patients undergoing IVF in comparison to standard large diameter needles.
Methods: We conducted a prospective pilot study of 21 consecutive favorable prognosis patients. In each patient one ovary was randomly allocated to retrieval with either a 20 G/ 35 mm (thin) or 17 G/ 35 mm (standard) needle, the other ovary was then retrieved with the opposite needle.
Results: The standard diameter needle was used to collect a total of 215 oocytes from 355 aspirated follicles (60.6%) compared to 203 oocytes from 352 aspirated follicles (57.7%) with the thinner needle (p=0.23). Stratifying outcomes by anti-Müllerian hormone (AMH), as indicator of ovarian reserve, and by body mass index (BMI) the oocyte yields, still, did not differ (AMH, r (17)=0.20, p=0.44; BMI, r (17) =0.02, p=0.96). Outcomes also did not vary among women with diminished ovarian reserve (p=0.17) and in women with normal ovarian reserve (p=1.00). Operating time was, however, significantly increased by 3.3 minutes per ovary (z=3.08, p=0.002) with the thinner needle.
Conclusions: Needle diameter does not affect oocyte yield, including in obese patients and patients with diminished ovarian reserve. Thinner needles appear to significantly prolong operating time.
VIDEO: A pilot trial of large versus small diameter needles for oocyte retrieval
Recorded on: Friday, April 26, 2013